Pamela L. Scheinman, Marc Vocanson, Ari M. Goldminz, Hyo-Eun Kwon, Hye-Jin Ahn, Min Kyung Shin, Stephan Weidinger, Lisa A. Beck, Alan D. Irvine, Young Jae Kim, Dong Jun Lim, Chong Hyun Won, Vasco Silva-Neves, Vitor Hugo, Miguel Pais-Vieira, Mario Mastrocola, Georg Matziolis, Henk Eijer, Julie Bruce, Blessing Oyedemi, Freya Harrison, Young-Je Kim, Mi Ji Choi, Beom Joon Kim, Raiyyan Aftab, Vikash H. Dodhia, Ryckie G. Wade, Scientific Reports volume11, Articlenumber:23762 (2021) These may include: Post-surgical rashes often go away when your skin is no longer in contact with the irritant. Surgiseal and LiquiBand were applied to two thin layers with a drying time of 30 to 60s between layers to enable polymerization, and Dermabond Prineo was applied with the same process to a mesh. 0000007745 00000 n No history of previous extended contact with acrylate glues, such as Superglue, artificial nail or eyelash adhesives or dental treatment requiring use of adhesives. She was afebrile and looked well. w5P 6 5N,i5E$3011aeax0d2b fc2ba41q?g+3dQ2 /:+c=2F-x..FDtT81a.Q|,/1E0|b She was afebrile. This can indicate infection, which needs to be treated right away. Emerg. Figure 2. Twenty of 739 (2.7%) patients using 2-octyl cyanoacrylate and nine of 406 (2.2%) patients using n-butyl cyanoacrylate showed ACD. Advanced knowledge sharing through global A 36-year-old white woman on postoperative day four. Extensive exposure to these sources of cyanoacrylate adhesives should be investigated before the decision is made to use Dermabond for surgical skin closure as they may predispose the patient to allergic reaction. Treatment is simple and most cases will resolve within a few weeks. The authors describe the first case series of ACD to Dermabond Prineo where patch testing confirmed the diagnosis in all patients. Generally, very few complications are associated with Dermabond and are usually related to application techniques. Afifi, Ahmed M. A severe allergic reaction can be seen; erythema and pruritis are both present along the incisions where Dermabond was applied. Am. An official website of the United States government. Patch Testing Ingredients of Dermabond and Other Cyanoacrylate-Containing Adhesives. Anonymity, Obligation to This report describes a rare case of a diffuse cutaneous allergic reaction to Dermabond following its use to close a surgical incision, its prompt identification, and treatment after presentation to an emergency department. 2021 Mar 24;13(3):e14090. Ther. 156, 577578 (2021). hb``d``;d|gb@ !; M$i``H~ 8Lt:$SuO8u$iHxrNDGQIgIB4YA]HN[RR1(z/o>O:Z)wSQ> J:::2 A case of contact dermatitis syndrome caused by Dermabond, followed by contact dermatitis caused by false eyelash glue and Aron Alpha glue: possibility of cross-reactions among cyanoacrylates. 8600 Rockville Pike We identified patients with positive patch test results for Dermabond and evaluated their results concerning (meth)acrylates and ethyl cyanoacrylate adhesive. Use the Previous and Next buttons to navigate the slides or the slide controller buttons at the end to navigate through each slide. Within six hours of receiving steroids, the erythema and pruritis were improved. This report describes a rare case of a diffuse cutaneous allergic reaction to Dermabond following its use to close a surgical incision, its prompt identification, and treatment after presentation to an emergency department. Academic Pulmonary Sleep Medicine Physician Opportunity in Scenic Central Pennsylvania, MEDICAL MICROBIOLOGY AND CLINICAL LABORATORY MEDICINE PHYSICIAN, CLINICAL CHEMISTRY LABORATORY MEDICINE PHYSICIAN. Emerg. Shaw, Daniel W. J. Arthroplasty 28, 553556 (2013). Background: The Dermabond (2-octyl cyanoacrylate) is a commonly used skin adhesive in plastic surgery. The use of Dermabond for surgical or traumatic wound closure was first approved in the United States by the FDA for human use in 1998. We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Provided by the Springer Nature SharedIt content-sharing initiative. 0000020617 00000 n 121 0 obj <> endobj As these values did not differ from those of all patients with possible risk factors (p=0.857 and 0.955, respectively), we concluded that previously known risk factors for type IV hypersensitivity did not significantly affect the incidence of ACD in topical skin adhesives. In some cases, your doctor may want to perform a skin biopsy as well. Table 1. While your rash may resolve quickly, you may need to change bandages or medications your doctor has prescribed. Article Google Scholar Anaphylactic allergic reaction, throat closure and systemic pruritus, has been noted following exposure to aspirin and codeine approximately 20 years prior. Epub 2021 Dec 16. Search for other works by this author on: Allergic contact dermatitis after postsurgical repair with 2-octylcyanoacrylate, FDA summary memo: General and Plastic Surgery Devices Advisory Committee (Panel) Meeting, August 25, 2006, A prospective comparison of octyl-2-cyanoacrylate and suture in standardized facial wounds, Use of 2-octyl-cyanoacrylate skin adhesive (Dermabond) for wound closure following reduction mammaplasty: A prospective, randomized intervention study, Ectopic contact dermatitis from ethyl cyanoacrylate instant adhesives, Contact dermatitis to ethyl-cyanoacrylate-containing glue, 10 years of patch testing with the (meth)acrylate series, Foreign body reaction after usage of tissue adhesives for skin closure: A case report and review of the literature, 2009 American Society for Aesthetic Plastic Surgery, Ultrasound Calculation of Fat Volume for Liposuction: A Clinical Software Validation, Opioid Prescribing Patterns in Body Contouring Surgery, Perspectives on Cybersecurity and Plastic Surgery: A Survey of Plastic Surgeons and Scoping Review of the Literature, Alternative Abdominal Wall Plication Techniques: A Review of Current Literature, Repair of Congenitally Defective Type of Earlobe Clefts With Residual Lobular Tissue: A Convenient and Effective Surgical Technique, https://doi.org/10.1016/j.asj.2009.02.019, http://www.fda.gov/ohrms/dockets/ac/06/briefing/2006-4233b2_01.pdf, Receive exclusive offers and updates from Oxford Academic, Simultaneous Breast Augmentation and Mastopexy. Bethesda, MD 20894, Web Policies Off-label medical use was widespread in many surgical specialties and dentistry by the 1980s especially throughout Europe. Clipboard, Search History, and several other advanced features are temporarily unavailable. J. The Bactrim DS was continued for one week because of the broken skin and the danger of superinfection. 0000068378 00000 n J. Bhargava K, White JM, White IR (2012) Eyelid allergic contact dermatitis caused by ethyl cyanoacrylate-containing eyelash adhesive. Surg. 2009 Jul-Aug;29(4):314-6. doi: 10.1016/j.asj.2009.02.019. There are some reports in the literature regarding Dermabond associated contact dermatitis. Department of Orthopedic Surgery, Korea University Guro Hospital, 148 Gurodong-ro, Guro-gu, Seoul, 08308, Republic of Korea, Young Hwan Park,Jeong Seok Choi,Jung Woo Choi&Hak Jun Kim, You can also search for this author in The patient's husband eventually excised the residual Dermabond and reclosed the wound. Cochrane Database Syst Rev. Strategic Goals and In vivo study of wound bursting strength and compliance of topical skin adhesives. Physical examination of the surgical incision sites revealed that they were all clean dry and intact. 0000060590 00000 n In this retrospective study, 577 patch tested patients were included. official website and that any information you provide is encrypted At-home therapies for eczema and dermatitis. Dermabond is a liquid adhesive that contains the monomer of 2-octyl cyanocrylate (at a concentration of 94%). 2019 Jan;35(1):75-77. doi: 10.1097/PEC.0000000000000994. . The next morning, with worsening erythema and itching, she was seen in the emergency room by the surgeon. Internet Explorer). Interv. By submitting a comment you agree to abide by our Terms and Community Guidelines. (2013) Robotically assisted vs laparoscopic hysterectomy among women with benign gynaecologic disease. This can include contact with surgical instruments or supplies that are not hypoallergenic, such as bandages, surgical glue, or antiseptic solutions. The authors declare no competing interests. ACD to topical skin adhesives usually presents as a self-limiting urticarial eruption near the incision site and subsides after proper local management. 0000098813 00000 n Objectives, Submission, Review, & 0000004181 00000 n Hysterectomy Recovery (post hysterectomy). and Injury 49, 19421946 (2018). Liquid 2-octyl cyanoacrylate and n-butyl cyanoacrylate monomers are commonly used ingredients for topical skin adhesives because they polymerize into solid chains upon contact with the wound surface and hold wound edges together14. Infect. This second exposure to Dermabond caused an intense contact dermatitis that readily resolved with steroid use. Join to Ask Your Questions and Receive Hysterectomy Checkpoints! Zwemer, Catherine Acad. MeSH Surgical wound closure by staples or sutures? In short, jock itch can spread between, Keloids can appear on your ear in response to any type of wound, including a piercing. From the Division of Plastic Surgery, Robert Wood Johnson Medical School, New Brunswick, NJ. The number is still staggering even though some estimate that the number of hysterectomies has been steadily declining over the last decade from a peak of 681,234 performed in 2002 to 433,621 cases reported in 2010. Contraindications to Dermabond use include cyanoacrylate or formaldehyde allergy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The adhesive property of the compound methyl 2-cyanoacrylate was first described in the literature by H.W. Nunley, Julia Hysterectomy Recovery (post hysterectomy), HysterSisters Takes On Partner To Manage Continued Growth And Longevity. Lee E, Elzomor A, Zwemer C, Chen A, Thakkar PG. Type IV hypersensitivity reactions following Dermabond adhesive utilization in knee surgery: A Report of Three Cases. 0000010096 00000 n The use of 2-octyl cyanoacrylate (Dermabond; Ethicon, Somerville, NJ) for wound closure is increasingly popular. Problems with Dermabond are generally related to application techniques and rarely relate to the chemical nature of the adhesive. Dermabond-induced ACD is apparently characterized by a high prevalence of primary sensitization at first exposure to Dermabond, secondary generalization is frequent, and most patients show cross-reactivity to ethyl cyanoacrylate. Bethesda, MD 20894, Web Policies JAMA Surg. doi: 10.7759/cureus.14090. Unable to load your collection due to an error, Unable to load your delegates due to an error. Collaborations, Submit Anyone ever had allergic reaction to Enjuvia? Pediatr Emerg Care. and Three additional trocars were placed in the right lower quadrant, left lower quadrant and at the umbilicus. 0000056163 00000 n Sunaga, Ataru Epub 2017 Jan 25. Radiol. After the surgical procedure of each patient, the fascia and subcutaneous layers were closed using 20 and 30 synthetic absorbable braided sutures. Lee, Esther H.J.K. Federal government websites often end in .gov or .mil. Rash 101 in adults: When to seek medical treatment. In the logistic regression analysis, age, sex, body mass index, diabetes, smoking, asthma, history of atopic dermatitis, history of contact dermatitis, neutrophil count, eosinophil count, and anatomical region did not show any correlation with the occurrence of allergic contact dermatitis (Table 2). for this article. Dermabond is a liquid topical skin adhesive containing a monomeric 2-octyl cyanoacrylate formulation and the colorant D&C Violet #2 which should slough off with desquamation of the epidermis 7-14 days after application. endstream endobj 122 0 obj <>>>/Lang(en-US)/Metadata 119 0 R/Names 123 0 R/Outlines 94 0 R/Pages 118 0 R/Type/Catalog/ViewerPreferences<>>> endobj 123 0 obj <> endobj 124 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/Tabs/W/Thumb 113 0 R/TrimBox[0.0 0.0 595.276 841.89]/Type/Page>> endobj 125 0 obj [126 0 R] endobj 126 0 obj <>/Border[0 0 0]/H/N/Rect[445.858 120.461 538.761 109.669]/Subtype/Link/Type/Annot>> endobj 127 0 obj <> endobj 128 0 obj <> endobj 129 0 obj [/ICCBased 153 0 R] endobj 130 0 obj <> endobj 131 0 obj <> endobj 132 0 obj <> endobj 133 0 obj <> endobj 134 0 obj <>stream For this reason, topical skin adhesives, which have the advantages of good scar cosmesis, infection prevention, easy skill acquisition, and lack of need for dedicated removal have begun to attract attention7,8,9,10,11,12,13. : A Review of the Literature. J. Arthroplasty 32, 37423747 (2017). Unauthorized use of these marks is strictly prohibited. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004287.pub4/ Farion K, Osmond MH, Hartling L, et al. Occupational asthma has also been linked to exposure to cyanoacrylate adhesives used to affix sculpted acrylic artificial nails in beauty salons [28]. Abdomen of 63-year-old patient on post-operative day 7 with sudden onset erythema and pruritus surrounding the umbilical, left upper abdominal, left lower abdominal and right lower abdominal 5-mm trocar sites. Hysterectomy Recovery (post hysterectomy) . Dermatologist evaluation confirmed the suspicion of an allergic reaction to Dermabond and recommended application of a thin topical layer of hydrocortisone 1% to affected areas 2-4 times per day. Fam. CAS Report of two cases. 39, 12831289 (2018). government site. Removal of the Dermabond was attempted, but the incision began to separate. Ghaferi, A. The https:// ensures that you are connecting to the Dermatitis 25, 99100 (2014). Cochetti, G. et al. Poore, Samuel O. A., Schwartz, T. A. 0000010011 00000 n Bone Jt. Nakagawa, Shiho Well go over the causes of an ear keloid before diving into. Diffuse Cutaneous Allergic Reaction to Dermabond. 0000047368 00000 n See additional information. trailer Contact dermatitis generally comes in two forms: Both of these conditions are usually localized to the areas of skin that come into contact with the specific substance/irritant. Additional components of Dermabond include plasticizers that aid in the flexibility of the wound during the healing process, stabilizers to prolong the shelf life, and polymerization inhibitors to delay the transition of the product from liquid to solid.2 The polymer hydrolyzes in the body, creating formaldehyde, which causes inflammation. HHS Vulnerability Disclosure, Help 2019. 5Tomb RR Lepoittevin JP Durepaire Fet al. But is jock itch contagious? 0000061344 00000 n 2-octyl cyanoacrylate; Dermabond; allergic contact dermatitis; ethyl cyanoacrylate; gel nails, (meth)acrylate; tissue adhesive. Sachse MM, Junghans T, Rose C, Wagner G (2013) Allergic contact dermatitis caused by topical 2-octyl-cyanoacrylate. Ferguson, J. W., Tripathi, D. & Hayes, P. C. Review article: The management of acute variceal bleeding. Dermabond was applied after her subcuticular suture closure. In this case, antibiotics were continued because the vesicular reaction created open wounds near the silicone implants; secondary infection of the dermatitis would have resulted in loss of the implants. Diffuse Cutaneous Allergic Reaction to Dermabond. Inflamed skin should be treated with hydrocortisone 1% applied topically two to four times per day until reaction abates. 0 It took over three weeks to go away. Quinn, J. et al. Post-surgical contact dermatitis is a localized rash that is almost always a reaction to something that came into contact with your skin. We avoid using tertiary references. I had a horrible reaction too. (2015). Ricci, Joseph A. Treatment for contact dermatitis is generally very simple. Technol. 0000008714 00000 n Dermatitis 2016; 27 (2):75. Please enable it to take advantage of the complete set of features! 2015;73(4):195-221. A rash around a surgical incision is fairly common. Our case, and the cases reviewed here, highlight the usual temporal presentation of allergic reaction to Dermabond. 2014;29(5):1-3. It. Medication for eczema and dermatitis. and transmitted securely. The rash should go away completely within a few weeks. HtV6}7Rno[o6HRvZJ\$*^${gg.`6{u~ujH`:vAUwK,7uXFqv?/#d3/~(8oVI#KG :8;+HjQ Responsibilities, Copyright & License As a retrospective study, informed consent was waived by Korea University Guro Hospital Institutional Review Board. On postoperative day one, she was seen routinely and was well. 0000062096 00000 n Park, Y.H., Choi, J.S., Choi, J.W. Consequently, despite the advantages of topical skin adhesives, many orthopedic surgeons still hesitate to use them due to unpredictable adverse effects. 2nd ed. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide, This PDF is available to Subscribers Only. Laparosc. Agreements, Confidentiality & The AADA also says that a patch test can be done to determine if the rash is allergic contact dermatitis. The site is secure. HysterSisters.com is a massive online community with over 475,000 members and over 5 million posts. A rash around a surgical incision is fairly common. However, there has never been a reported case resulting from use during gynaecologic surgery until now. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Objective: . Healthline Media does not provide medical advice, diagnosis, or treatment. Its a good idea to let your doctor know if you develop a rash after surgery. Sheikh, Mohammad Tafazul The .gov means its official. Jacoby, Sidney M. the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in This report describes a rare case of a diffuse cutaneous allergic reaction to Dermabond following its use to close a surgical incision, its prompt identification, and treatment after presentation to an emergency department. Commentary on: Does Implant Surface Texture Affect the Risk of Capsular Contracture in Subglandular Breast Augmentation and Breast Augmentation-Mastopexy? Call 911 if you have: Simple home and over-the-counter (OTC) treatments can treat contact dermatitis as well.
Chapel Hill Professors,
Patrick Riley Obituary,
Lien Karmique Flamme Jumelle,
Articles D